GST P1-1, Recombinant Human
SIGMA/GS70
Synonym: DFN7; FAEES3; GST3; GSTP; HEL-S-22; glutathione S-transferase pi
Product Type: Product-on-demand
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| assay | >95% (SDS-PAGE) |
| biological source | human |
| form | frozen liquid |
| mol wt | 23 kDa |
| Quality Level | 100  |
| recombinant | expressed in E. coli |
| specific activity | 60.45 units/mg protein |
| storage temp. | −70°C |
| Biochem/physiol Actions: | Glutathione S-transferase pi 1 (GSTP1) is an enzyme that in humans is encoded by the GSTP1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. |
| Biochem/physiol Actions: | This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. |
| General description: | using spectrophotometric determination of 1-chloro-2,4-dinitrobenze |
| Preparation Note: | The enzyme should be used by the end-user customer within 1 year of receipt. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| activity | specific activity: 60.45 units/mg protein |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |