Hemoglobin A2, Ferrous Stabilized human
SIGMA/H0266 - lyophilized powder
CAS Number: 9034-53-1
EC Number: 232-897-1
MDL Number: MFCD00131286
Product Type: Chemical
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| assay | 97-100% (agarose gel electrophoresis) |
| biological source | human |
| form | lyophilized powder |
| Quality Level | 200  |
| storage temp. | −20°C |
| suitability | suitable for electrophoresis and chromatography standard |
| technique(s) | immunofluorescence: suitable |
| UniProt accession no. | P69905  |
| Application: | Hemoglobin A2 was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay. |
| Application: | Hemoglobin A2, Ferrous Stabilized human has been used as a reference in reversed-phase high-performance liquid chromatography for quantifying δ-globin elution profile. It has also been used as calibrator in isotope dilution mass spectrometry (IDMS) measurements. |
| Biochem/physiol Actions: | Elevated levels of Hemoglobin A2 (HBA2) is observed in patients with β-thalassemia trait. |
| General description: | has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins). |
| General description: | Hemoglobin A2 (HBA2) is mapped to human chromosome 16p13.3. HBA2 is a minor hemoglobin component and comprises of two α and δ chains. |
| General description: | Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide. |
| Packaging: | Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946). |
| Preparation Note: | When reconstituted with buffer, gives >90% ferrous hemoglobin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97-100% (agarose gel electrophoresis) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |