Hemoglobin A0, Ferrous Stabilized human
SIGMA/H0267 - lyophilized powder
Synonym: Hemoglobin A0 Ferrous Stabilized; Hemoglobin-A0
CAS Number: 54651-57-9
EC Number: 259-278-9
MDL Number: MFCD00131287
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H0267-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H0267-25MG
| assay | 97-100% (agarose gel electrophoresis) |
| biological source | human |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | H2O: soluble 20 mg/mL |
| storage temp. | −20°C |
| suitability | suitable for electrophoresis and chromatography standard |
| technique(s) | immunofluorescence: suitable |
| UniProt accession no. | P68871  |
| Application: | Hemoglobin A0, ferrous stabilized human has been used: • as the non-fluorescent absorber in the preparation of tissue-mimicking phantoms • to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype • to study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF |
| Application: | Hemoglobin A0 was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay. |
| Biochem/physiol Actions: | Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins). |
| General description: | Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide. |
| Packaging: | Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946). |
| Preparation Note: | When reconstituted with buffer, gives >85% ferrous hemoglobin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97-100% (agarose gel electrophoresis) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |