Heptakis(2,6-di-O-methyl)-β-cyclodextrin

SIGMA/H0513

Synonym: DM-β-CD; DM‐β‐CyD; heptakis-(2,6-O-Dimethyl)-β-cyclodextrin; 2,6-Di-O-methyl-β-cyclodextrin; Dimethyl β-cyclodextrin

CAS Number: 51166-71-3
Empirical Formula (Hill Notation): C₅₆H₉₈O₃₅
Molecular Weight: 1331.36
MDL Number: MFCD00011616
Linear Formula: C₅₆H₉₈O₃₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-H0513-1G	1 g	$36.50 1/EA	Add To Favorites
45-H0513-5G	5 g	$173.00 1/EA	Add To Favorites

ATR-IR Spectra for 2,6-Di-O-methyl-β-cyclodextrin.

FT-NMR Spectra for 2,6-Di-O-methyl-β-cyclodextrin.

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H0513-1G

Properties
Descriptions
Safety Info.
Basic Data

biological source	synthetic
form	powder
InChI	1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1
InChI key	QGKBSGBYSPTPKJ-UZMKXNTCSA-N
Quality Level	200
SMILES string	COC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](OC)[C@H](O[C@@H]3COC)O[C@H]4[C@H](O)[C@@H](OC)[C@H](O[C@@H]4COC)O[C@H]5[C@H](O)[C@@H](OC)[C@H](O[C@@H]5COC)O[C@H]6[C@H](O)[C@@H](OC)[C@H](O[C@@H]6COC)O[C@H]7[C@H](O)[C@@H](OC)[C@H](O[C@@H]7COC)O[C@H]8[C@H](O)[C@@H](OC)[C@H](O[C@@H]8COC)O[C@H]1[C@H](O)[C@H]2OC

Analysis Note:	Impurities are over-methylated homologs, primarily hexakis(2,6-di-O-methyl)-(2,3,6-tri-O-methyl)-β-cyclodextrin.
Application:	Heptakis(2,6-di-O-methyl)-β-cyclodextrin may be used: • To measure the equilibrium constant of its complexes with various enantiomeric pairs of chiral nitroxides by electron paramagnetic resonance (EPR) spectroscopy. • To study the crystal structure of its complex with n-butyl acrylate and isobornyl acrylate using X-ray diffraction (XRD). • As a chiral selector to resolve amphetamine related drugs by capillary zone electrophoresis.
Application:	Reactant involved in: • Physicochemical studies of inclusion complexes • Probing diffusion and single molecule interactions with reconstituted membrane proteins • Interactions with micelles causing micellar rupture • Studying cellular transport, used as a cell penetration enhancer • Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability • Interactions with cholesterol
General description:	Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds.
Packaging:	1, 5 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

12352005

To Order From a Quote