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Hemicholinium-3

SIGMA/H108 - solid, ≥95% (HPLC)

Synonym: 2,2′-(4,4′-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium bromide)

CAS Number: 312-45-8
Empirical Formula (Hill Notation): C24H34Br2N2O4
Molecular Weight: 574.35
EC Number: 206-227-3
MDL Number: MFCD00011978
Linear Formula: C24H34Br2N2O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H108-100MG 100 mg
 $104.00
1/EA		 Add To Favorites
45-H108-500MG 500 mg
 $500.00
1/EA		 Add To Favorites

 

assay ≥95% (HPLC)
color white
form solid
InChI 1S/C24H34N2O4.2BrH/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24;;/h5-12,27-28H,13-18H2,1-4H3;2*1H/q+2;;/p-2
InChI key OPYKHUMNFAMIBL-UHFFFAOYSA-L
Quality Level 100 
SMILES string [Br-].[Br-].C[N+]1(C)CCOC(O)(C1)c2ccc(cc2)-c3ccc(cc3)C4(O)C[N+](C)(C)CCO4
solubility ethanol: 1.3 mg/mL
  H2O: 10 mg/mL
Application: Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells.
Biochem/physiol Actions: Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain.
Features and Benefits: This compound is featured on the Acetylcholine Synthesis and Metabolism  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Purity ≥95% (HPLC)
UNSPSC 12352200

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