(R)(−)-α-Methylhistamine dihydrochloride
SIGMA/H128 - solid, ≥98% (HPLC)
Synonym: (R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride
CAS Number: 75614-89-0
Empirical Formula (Hill Notation): C6H11N3 · 2HCl
Molecular Weight: 198.09
MDL Number: MFCD00083176
Linear Formula: C6H11N3 · 2HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to off-white |
| form | solid |
| InChI | 1S/C6H11N3.2ClH/c1-5(7)2- |
| InChI key | IZHCNQFUWDFPCW-ZJIMSODOSA |
| optical activity | [α]22/D −4°, c = 0.8 in H2O(lit.) |
| Quality Level | 100 ![]() |
| SMILES string | Cl.Cl.C[C@@H](N)Cc1c[nH]c |
| solubility | H2O: soluble |
| storage condition | desiccated |
| Application: | (R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines. |
| Biochem/physiol Actions: | (R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H3 histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release. |
| Packaging: | 100 mg in poly bottle |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352116 |


