Hydralazine hydrochloride
SIGMA/H1753
Synonym: 1-
CAS Number: 304-20-1
Empirical Formula (Hill Notation): C8H8N4 · HCl
Molecular Weight: 196.64
EC Number: 206-151-0
MDL Number: MFCD00135998
Linear Formula: C8H8N4 · HCl
Product Type: Chemical
ATR-IR Spectra for Hydralazine hydrochloride.
FT-NMR Spectra for 1-Hydrazinophthalazine hydrochloride.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H1753-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H1753-5G
| assay | ≥99% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C8H8N4.ClH/c9-11-8-7-4 |
| InChI key | SECXUXOCDLQOBI-MKFZHGHUSA |
| mp | 273 °C |
| Quality Level | 100  |
| SMILES string | Cl[H].NN=C1/N=NC=C2C=CC= |
| solubility | water: 50 mg/mL |
| Application: | Hydralazine hydrochloride has been used: • as a vasodilator to study its effects on hypertension in T-cell frequencies in juvenile rats • as a semicarbazide-sensitive amine oxidase (SSAO) inhibitor to study its effects on myocardial ischemia-reperfusion (I/R) injury • as a vasodilator to study its effects on insulin secretion and glucose tolerance |
| Biochem/physiol Actions: | Hydralazine hydrochloride has therapeutic effects against heart failure and high blood pressure. |
| Biochem/physiol Actions: | Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; antihypertensive; semicarbazide-sensitive amine oxidase inhibitor. |
| Features and Benefits: | This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 10, 50 g in poly bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H315 - H319 - H335 |
| Precautionary statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (TLC) |
| mp | 273 °C |
| UNSPSC | 12352200 |