Advanced Search



3-Hydroxy-DL-kynurenine

SIGMA/H1771

Synonym: α,2-Diamino-3-hydroxy-γ-oxobenzenebutanoic acid

CAS Number: 484-78-6
Empirical Formula (Hill Notation): C10H12N2O4
Molecular Weight: 224.21
MDL Number: MFCD00047832
Linear Formula: C10H12N2O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H1771-25MG 25 mg
 $189.00
1/EA		 Add To Favorites
45-H1771-100MG 100 mg
 $566.00
1/EA		 Add To Favorites
45-H1771-250MG 250 mg
 $1210.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H1771-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H1771-250MG

 

assay ≥98% (TLC)
form powder
InChI 1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16)
InChI key VCKPUUFAIGNJHC-UHFFFAOYSA-N
Quality Level 200 
SMILES string NC(CC(=O)c1cccc(O)c1N)C(O)=O
solubility 1 M HCl: 49.00-51.00 mg/mL, clear to very slightly hazy
storage temp. 2-8°C
Application: 3-Hydroxy-DL-kynurenine has been used:
• as a substrate for the recombinant human kynureninase assay
• as a reference standard in tandem mass spectrometry (MS/MS) analysis
• as a control for quantifying serum 3-Hydroxy-DL-kynurenine levels in diabetic retinopathy patients
Biochem/physiol Actions: 3-Hydroxy-DL-kynurenine (3-HKYN) has antioxidant functionality and prevents lipid peroxidation in cerebral cortex. It may modulate synaptic neurotransmission. The levels of 3-HKYN is elevated in Huntington′s disease. However, its role in neurodegenerative diseases is still not understood well. Kynurenine metabolism is linked with glutamatergic neurotransmission and the level of 3-HKYN is linked to the pathophysiology of schizophrenia.
General description: 3-Hydroxy-DL-kynurenine is a tryptophan metabolite with a molecular weight corresponding to 224Da. It is a chromophore or hydrophilic yellow compound present in the lens of the eye. 3-Hydroxy-DL-kynurenine is synthesized from kynurenine by the action of enzyme kynurenine 3-monooxygenase (KMO). It is metabolized to 3-hydroxyanthranilic acid and xanthurenic acid in the presence of enzymes kynureninase and kynurenine aminotransferases, respectively.
Packaging: 25, 100, 250 mg in poly bottle
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352204

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top