Hemoglobin from bovine blood
SIGMA/H2500 - lyophilized powder
Synonym: Bovine hemoglobin; Hb; Methemoglobin
CAS Number: 9008-02-0
MDL Number: MFCD00131282
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H2500-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H2500-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H2500-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H2500-1G
| biological source | bovine blood |
| form | lyophilized powder |
| mol wt | Mr ~64500 |
| Quality Level | 300  |
| storage temp. | 2-8°C |
| technique(s) | MALDI-TOF: suitable |
| UniProt accession no. | P01966  |
| P02070 |
|
| P02081 |
|
| P06642 |
|
| P06643 |
| Application: | Hemoglobin from bovine blood has been used in: • standard curve generation for the quantification intraparenchymal hemorrhage and parenchymal hemorrhage in spinal cord homogenate using Drabkin′s assay, Quadrupole-Ion Mobility-Time-of-Flight mass spectrometery • the generation of molecularly imprinted polymers (MIPs) to mimic high molecular-weight polyethylene glycol (PEG) in crystallization studies |
| Application: | The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials. |
| Biochem/physiol Actions: | Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide. Bovine hemoglobin is used in the generation of hemoglobin-vesicles (HbV) for oxygen transport. It is thermally stable and displays high affinity to oxygen when compared to human hemoglobin. Bovine hemoglobin interacts with synthetic and azo dyes. Polymerized forms of bovine haemoglobin is recommended for treating autoimmune hemolytic anemia. |
| Biochem/physiol Actions: | Oxygen transporter, NO scavenger |
| Biochem/physiol Actions: | Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues. |
| Disclaimer: | Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin. |
| General description: | Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is a globular protein with α and β chains with each 141 and 146 amino acids, respectively. It exists as a tetramer with each monomer having heterocyclic porphyrin ring with iron constituting the heme. |
| Packaging: | 1, 5, 10, 25 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |