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6β-Hydroxytestosterone

SIGMA/H2898 - ≥97% (HPLC)

Synonym: 4-Androstene-6β,17β-diol-3-one; 6β, 17β,-Dihydroxyandrost-4-en-3-one

CAS Number: 62-99-7
Empirical Formula (Hill Notation): C19H28O3
Molecular Weight: 304.42
MDL Number: MFCD00171612
Linear Formula: C19H28O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-H2898-5MG 5 mg
$180.00
1/EA
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45-H2898-25MG 25 mg
$619.00
1/EA
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assay ≥97% (HPLC)
drug control regulated under CDSA - not available from Sigma-Aldrich Canada
form powder
InChI 1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1
InChI key XSEGWEUVSZRCBC-ZVBLRVHNSA-N
Quality Level 200 
shipped in ambient
SMILES string C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
solubility methanol: 50 mg/mL, clear, colorless
sterility non-sterile
storage temp. room temp
Application: 6β-Hydroxytestosterone has been used as a standard in high-performance liquid chromatography (HPLC) analysis to measure testosterone 6 β -hydroxylase activity in rat liver microsomes, and measure cytochrome P450 3A (CYP3A) activity in the intestinal spheroid model.
Biochem/physiol Actions: 6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic.
Biochem/physiol Actions: 6β-Hydroxytestosterone is a metabolite generated by brain testosterone cytochrome P450 1B1 (CYP1B1). It may elicit angiotensin II-induced neurogenic hypertension and inflammation in male mice.
Packaging: 5, 25 mg in serum bottle
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H351 - H360
Precautionary statements P201 - P308 + P313
Hazard Codes T
Risk Statements 61-40
Safety Statements 22-36/37/39
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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