Halopemide

SIGMA/H3041 - ≥98% (HPLC)

Synonym: N-(2-(4-(5-Chloro-2-oxo-1-benzimidazolinyl)piperidino)ethyl)-p-fluorobenzamide

CAS Number: 59831-65-1
Empirical Formula (Hill Notation): C₂₁H₂₂ClFN₄O₂
Molecular Weight: 416.88
MDL Number: MFCD00866684
Linear Formula: C₂₁H₂₂ClFN₄O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-H3041-25MG	25 mg	$668.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	off-white
form	powder
InChI	1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)
InChI key	NBHPRWLFLUBAIE-UHFFFAOYSA-N
Quality Level	100
SMILES string	Fc1ccc(cc1)C(=O)NCCN2CCC(CC2)N3C(=O)Nc4cc(Cl)ccc34
solubility	DMSO: >10 mg/mL
storage temp.	2-8°C

Application:	Halopemide, a non-specific phospholipase D (PLD) antagonist, may be used with selective PLD antagonists (CAY10593, a PLD1 antagonist; CAY10594 or ML298, selective PLD2 antagonist) to help define the role and physiological effects regulated by phospholipase D enzymes. Halopemide may be used as the basis of the design and development of more selective PLD antagonists.
Biochem/physiol Actions:	Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor.
Biochem/physiol Actions:	Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352204

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