Haptoglobin from pooled human plasma
SIGMA/H3536 - ≥95% (SDS-PAGE), lyophilized powder
Synonym: Haptoglobin from human plasma
CAS Number: 9087-69-8
MDL Number: MFCD00131259
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | ≥95% (SDS-PAGE) |
| biological source | human plasma (pooled) |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | H2O: soluble 10 mg/mL |
| storage temp. | −20°C |
| technique(s) | activity assay: suitable |
| UniProt accession no. | P00738  |
| Application: | Haptoglobin was used to study induction of the acrosome reaction in sperm. Exposure to low temperature increases their rate of fusion with zona-free hamster oocytes. |
| Biochem/physiol Actions: | Functions by binding to plasma hemoglobin (from hemolysis). The complex is removed from the circulation, by binding to CD163 receptors on macrophages, to salvage iron and prevent oxidative damage. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins.The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains. |
| General description: | Haptoglobin is an acute phase protein that scavenges hemoglobin released into the circulation. Haptoglobin, the plasma protein with highest binding affinity to hemoglobin, is mainly expressed in the liver. |
| Other Notes: | Occurs as 3 major phenotypes: type 1-1, type 2-1, type 2-2. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |