Hemoglobin equine
SIGMA/H4632 - lyophilized powder
Synonym: Hb
CAS Number: 9047-09-0
MDL Number: MFCD00131282
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H4632-10G
| biological source | horse |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | H2O: soluble 10 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | protein quantification: suitable |
| UniProt accession no. | P01958  |
| P02062 |
| Application: | Hemoglobin equine has been used as a standard protein: • to test solid-film sampling methodology in Fourier transform infrared spectroscopy (FT-IR) for protein secondary structure determination • in capillary reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) post enzymatic digestion • for quantification of hemoglobin content from the planktonic crustacean, Daphnia magna |
| Biochem/physiol Actions: | Hemoglobin is the most important respiratory protein of vertebrates by its ability to transport oxygen from the lungs to body tissues and to facilitate the return transport of carbon dioxide. The ferrous-ferric (Fe2+/Fe3+) balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to nitric oxide (NO), a vasodilator which enhances blood flow to oxygen-deprived tissues. The fetal and adult hemoglobin from horse display differences in their affinity towards 2,3-diphosphoglycerate (2,3-DPG). Mutation in the globin gene is implicated in sickle cell anemia. |
| Biochem/physiol Actions: | Oxygen transporter, NO scavenger |
| Disclaimer: | Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin. |
| General description: | Hemoglobin is the major component of red blood cells and is responsible for their red color. Its normal concentration in erythrocytes is 34%. The structure of horse hemoglobin was elucidated first. It comprises heme (iron protoporphyrin IX group) and four polypeptide chains. The fetal and adult hemoglobin of horse are structurally identical. |
| Packaging: | 10 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |