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Hydrocortisone 21-hemisuccinate sodium salt

SIGMA/H4881 - ≥90% (HPLC)

Synonym: 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt; Cortisol 21-hemisuccinate sodium salt

CAS Number: 125-04-2
Empirical Formula (Hill Notation): C25H33NaO8
Molecular Weight: 484.51
EC Number: 204-725-5
MDL Number: MFCD00069472
Linear Formula: C25H33NaO8
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-H4881-100MG 100 mg
$39.90
1/EA
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45-H4881-1G 1 g
$200.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H4881-100MG

 

assay ≥90% (HPLC)
biological source synthetic (organic)
form powder
InChI 1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
InChI key HHZQLQREDATOBM-CODXZCKSSA-M
Quality Level 200 
shipped in ambient
SMILES string O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]
solubility water: 50 mg/mL, clear, colorless to faintly yellow
storage temp. −20°C
Application: Hydrocortisone 21-hemisuccinate sodium salt has been used:
• as a component of the maturation medium for hepatic differentiation
• in the corticosterone (CORT) treatment to study its effect on astrocyte-like neural stem cell proliferation in the area postrema of the adult mouse brain
• in cortisol incubation experiments to study the effect of cortisol on the expression and function of sodium-chloride cotransporter (NCC) in zebrafish embryos

Packaging: 1 g in glass bottle
Packaging: 100 mg in glass bottle
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361d
Precautionary statements P201 - P308 + P313
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90% (HPLC)
Storage Temp. −20°C
UNSPSC 12352209

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