20-Hydroxyecdysone

SIGMA/H5142 - ≥93% (HPLC), powder

Synonym: β-Ecdysone; 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one; Ecdysterone; Insect moulting hormone; Polypodine A

CAS Number: 5289-74-7
Empirical Formula (Hill Notation): C₂₇H₄₄O₇
Molecular Weight: 480.63
MDL Number: MFCD00036740
Linear Formula: C₂₇H₄₄O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-H5142-5MG	5 mg	$217.00 1/EA	Add To Favorites
45-H5142-10MG	10 mg	$413.00 1/EA	Add To Favorites
45-H5142-25MG	25 mg	$896.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	agriculture environmental
assay	≥93% (HPLC)
color	white to off-white
form	powder
InChI	1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
InChI key	NKDFYOWSKOHCCO-YPVLXUMRSA-N
Quality Level	100
shipped in	ambient
SMILES string	[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@@](C)(O)[C@H](O)CCC(C)(C)O
solubility	alcohol: soluble
sterility	non-sterile
storage temp.	−20°C

Application:	20-Hydroxyecdysone has been used: • in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta • in Schneider′s medium to reproduce ex-vivo imaginal disc eversion • as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
Biochem/physiol Actions:	20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
Packaging:	10, 25 mg in poly bottle
Packaging:	5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥93% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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