L-Histidine monohydrochloride monohydrate
SIGMA/H5659 - from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
Synonym: L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
CAS Number: 5934-29-2
Empirical Formula (Hill Notation): C6H9N3O2 · HCl · H2O
Molecular Weight: 209.63
MDL Number: MFCD00151027
Linear Formula: C6H9N3O2 · HCl · H2O
Product Type: Chemical
FT-IR Raman Spectra for ʟ-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride.
FT-IR Spectra for ʟ-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: H5659-100G
This image depicts SKU: H5659-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: H5659-25G
This image depicts SKU: H5659-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: H5659-1KG
This image depicts SKU: H5659-1KG
| agency | meets EP testing specifications |
| assay | 98.5-101.0% |
| biological source | non-animal source |
| color | white |
| form | crystalline powder |
| impurities | endotoxin, tested |
| InChI | 1S/C6H9N3O2.ClH.H2O/c7-5( |
| InChI key | CMXXUDSWGMGYLZ-XRIGFGBMSA |
| mp | 254 °C (dec.) (lit.) |
| product line | BioXtra |
| Quality Level | 300  |
| SMILES string | O.Cl.N[C@@H](Cc1c[nH]cn1) |
| solubility | H2O: 100 mg/mL |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium. |
| Application: | L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses. |
| Biochem/physiol Actions: | L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 25, 100 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98.5-101.0% |
| mp | 254 °C (dec.) (lit.) |
| UNSPSC | 12352209 |