7β-Hydroxycholesterol

SIGMA/H6891 - ≥95%

Synonym: 5-Cholestene-3β,7β-diol

CAS Number: 566-27-8
Empirical Formula (Hill Notation): C₂₇H₄₆O₂
Molecular Weight: 402.65
MDL Number: MFCD00058406
Linear Formula: C₂₇H₄₆O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-H6891-1MG	1 mg	$223.00 1/EA		Add To Favorites
45-H6891-5MG	5 mg	$721.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	powder
functional group	hydroxyl
InChI	1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3
InChI key	OYXZMSRRJOYLLO-UHFFFAOYSA-N
Quality Level	200
shipped in	ambient
SMILES string	[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C
storage temp.	room temp

Application:	7β-hydroxycholesterol was used to study oxysterol-induced apoptosis in human endothelial cells.
Biochem/physiol Actions:	7β-Hydroxycholesterol is an oxysterol, the enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis.
Packaging:	1, 5 mg in glass bottle
Packaging:	10 mg in poly bottle
Preparation Note:	7β-Hydroxycholesterol yields clear, colorless to faint yellow solution in ethanol, with or without heating.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	room temp
UNSPSC	12352211

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.