Macrophage Colony-Stimulating Factor human
SIGMA/H6916 - M-CSF, recombinant, expressed in HEK 293 cells, suitable for cell culture
Synonym: MCSF
MDL Number: MFCD00166591
Product Type: Chemical
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| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | lyophilized powder |
| manufacturer/tradename | HumanZyme |
| mol wt | dimer 35-40 kDa (glycosylated) |
| packaging | pkg of 10 μg |
| potency | ≤4 ng/mL EC50 |
| quality | endotoxin tested |
| Quality Level | 100  |
| recombinant | expressed in HEK 293 cells |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P09603  |
| Analysis Note: | The specific activity was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells (mouse myeloid Leukemia indicator cell line). |
| Biochem/physiol Actions: | Macrophage CSF (M-CSF) as a growth factor, stimulates the proliferation and differentiation of monocyte/macrophage-linea |
| General description: | M-CSF is encoded by the gene mapped to human chromosome 1p13.3. It is a glycosylated polypeptide, which exists as a homodimer. M-CSF is produced by macrophage, fibroblasts, lymphocyte and endothelial cells. |
| Legal Information: | HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc |
| Packaging: | 10 μg in poly bottle |
| Physical form: | Lyophilized from a 0.2 μm filtered solution of 1x PBS. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |