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(Hydroxypropyl)methyl cellulose

SIGMA/H8384 - viscosity 40-60 cP, 2 % in H2O(20 °C)(lit.)

Synonym: 2-Hydroxypropyl methyl cellulose ether

CAS Number: 9004-65-3
MDL Number: MFCD00131360
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H8384-25G 25 g
 $68.40
1/EA		 Add To Favorites
45-H8384-100G 100 g
 $172.00
1/EA		 Add To Favorites
45-H8384-250G 250 g
 $345.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H8384-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H8384-250G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H8384-25G

 

color beige
form powder
InChI 1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-
InChI key PUSNGFYSTWMJSK-GSZQVNRLSA-N
mol wt ~22 kDa
Quality Level 200 
SMILES string O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC
solubility water: 10 mg/mL, clear to slightly hazy
storage temp. room temp
viscosity 40-60 cP, 2 % in H2O(20 °C)(lit.)
Analysis Note: Normally contains some iron particles.
Application: Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.
Features and Benefits: Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.
Other Notes: To gain a comprehensive understanding of our extensive range of Polysaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
Packaging: 25, 100, 250 g in poly bottle
Preparation Note: This product is soluble in water (10 mg/ml). However, it is very important to thoroughly disperse the particles in water with agitation before they will dissolve. Otherwise, they will lump and form a gelatinous membrane around the internal particles, preventing them from wetting completely. There are four dispersion techniques commonly used to prepare solutions of hydroxypropylmethylcellulose: dispersion in hot water, dry blending, dispersion in non-solvent medium, and dispersion of surface-treated powders. (The last method is only for surface-treated powders).

Dispersion in hot water:
1. Heat approximately 1/3 the required volume of water to at least 90 oC.
2. Add the powder to the heated water with stirring or agitation.
3. Agitate the mixture until the particles are thoroughly wetted and evenly dispersed.
4. Add the remainder of the water (cold water) to lower the temperature of the dispersion. As the product cools, it will reach a temperature at which it becomes water soluble. It will then begin to hydrate and dissolve, increasing the viscosity of the solution.
5. Continue agitation for at least 30 minutes after the proper temperature is reached for solubility. The solution is now ready to use.

Dry blending:
1. Combine powder with other dry ingredients. The suggested ratio of dry powder to hydroxypropylmethylcellulose is 7:1 to 3:1.
2. Thoroughly blend the dry ingredients.
3. Add the dry mixture to water with agitation.
4. Agitate until the product has completed hydrated and the solution is consistently smooth. The solution is now ready for further processing/use.

Dispersion in non-solvent medium:
1. Hydroxypropylmethylcellulose may be dispersed in non-solvent media such as vegetable oil, polyethylene glycol, glycerin, corn syrup, and concentrated salt solutions. A ratio of 5-8 parts non-solvent to 1 part hydroxypropylmethylcellulose is recommended to obtain a liquid slurry.
2. Agitate the mixture until the particles are evenly dispersed.
3. This dispersion may be added to cold water or cold water may be added to the dispersion.
4. Continue mixing until the powder is completely hydrated and the solution is smooth. Additional ingredients may now be added to the formulation.
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. room temp
UNSPSC 12352201

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