5-Hydroxyindole-3-acetic acid
SIGMA/H8876 - ≥98% (HPLC), crystalline
Synonym: 5-HIAA
CAS Number: 54-16-0
Empirical Formula (Hill Notation): C10H9NO3
Molecular Weight: 191.18
EC Number: 200-195-4
MDL Number: MFCD00005639
Linear Formula: C10H9NO3
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to purple |
| form | crystalline |
| InChI | 1S/C10H9NO3/c12-7-1-2-9-8 |
| InChI key | DUUGKQCEGZLZNO-UHFFFAOYSA |
| mp | 161-164 °C (dec.) (lit.) |
| Quality Level | 200  |
| SMILES string | OC(=O)Cc1c[nH]c2ccc(O)cc1 |
| storage temp. | −20°C |
| Application: | 5-Hydroxyindole-3-acetic acid has been used as standard for the measurement of 5-HIAA in the brain tissue of mice using high performance liquid chromatography (HPLC). |
| Biochem/physiol Actions: | Major serotonin metabolite. |
| General description: | 5-Hydroxyindole-3-acetic acid (5-HIAA) is the catabolic end product of serotonin pathway. 5-HIAA is present in body fluids like cerebrospinal fluid (CSF), blood and urine. The expression levels of 5-HIAA is different among the normal and cancer patients. Sepiapterin reductase deficiency results in low level of 5-HIAA in CSF. 5-HIAA level is low in CSF in patients with bipolar 1 disorder with childhood attention-deficit hyperactivity disorder (ADHD). |
| Packaging: | 1 g in poly bottle |
| Packaging: | 100 mg in poly bottle |
| Packaging: | 500 mg in poly tube |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 161-164 °C (dec.) (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352106 |