Hydroxyzine dihydrochloride
SIGMA/H8885 - ≥97%
CAS Number: 2192-20-3
Empirical Formula (Hill Notation): C21H27ClN2O2 · 2HCl
Molecular Weight: 447.83
EC Number: 218-586-3
MDL Number: MFCD00058200
Linear Formula: C21H27ClN2O2 · 2HCl
Product Type: Chemical
| assay | ≥97% |
| form | powder |
| InChI | 1S/C21H27ClN2O2.2ClH/c22- |
| InChI key | ANOMHKZSQFYSBR-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | Cl[H].Cl[H].OCCOCCN1CCN(C |
| solubility | alcohol: soluble |
| chloroform: soluble | |
| H2O: soluble |
| Application: | Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats. |
| Biochem/physiol Actions: | Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery. |
| General description: | Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist. |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302 - H336 - H361d |
| Precautionary statements | P201 - P301 + P312 + P330 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% |
| UNSPSC | 12161501 |



