Hepatitis C virus core antigen
SIGMA/H9034 - ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
MDL Number: MFCD02264926
Product Type: Chemical
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| assay | ≥95% (SDS-PAGE) |
| concentration | ~1 mg/mL |
| mol wt | 22 kDa (plus 114 kDa galactosidse) |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −20°C |
| UniProt accession no. | G9G988  |
| L7S4V3 |
| Application: | Hepatitis core antigen (HCA) has been used as an analyte in enzyme-linked immunosorbent assay (ELISA) to study the mechanism of bovine serum albumin (BSA) blocking in common ELISA protocols. |
| Biochem/physiol Actions: | Hepatitis C virus core antigen (HCV-cAg) may be a less expensive way to diagnose active hepatitis C virus (HCV) infection in the hemodialysis (HD) population. |
| Biochem/physiol Actions: | Positive control for HCV antibodies. |
| Biochem/physiol Actions: | Reacts strongly with human HCV positive serum. |
| General description: | amino acids 2-192 of HCV polyprotein |
| General description: | Hepatitis C virus core antigen (HCV-cAg) is a well-preserved antigenic protein of the internal capsid. |
| General description: | Hepatitis C virus glycoprotein 1 (HCVgp1), also referred to as polyprotein, is crucial for the induction of double-membrane vesicles, sites of HCV RNA amplification. The amino terminal of polyprotein contains the structural proteins core, envelope protein 1 (E1) and E2. The proteolytic cleavage of polyprotein results in the formation of 10 mature viral proteins which are needed for viral replication and assembly. |
| Other Notes: | HCV core antigen [2-192]-Galactosidase-tag |
| Physical form: | Solution in 8 M Urea, 20 mM Tris-HCl, pH 8.0, 10 mM 2-mercaptoethanol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |