Serotonin hydrochloride

SIGMA/H9523 - powder

Synonym: 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride; 5-HT; 5-Hydroxytryptamine hydrochloride

CAS Number: 153-98-0
Empirical Formula (Hill Notation): C₁₀H₁₂N₂O · HCl
Molecular Weight: 212.68
MDL Number: MFCD00012686
Linear Formula: C₁₀H₁₂N₂O · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-H9523-25MG	25 mg	$55.40 1/EA	Add To Favorites
45-H9523-100MG	100 mg	$148.00 1/EA	Add To Favorites
45-H9523-250MG	250 mg	$311.00 1/EA	Add To Favorites
45-H9523-1G	1 g	$933.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H9523-25MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
color	white to off-white
description	Drug Control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
drug control	Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
form	powder
InChI	1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H
InChI key	MDIGAZPGKJFIAH-UHFFFAOYSA-N
mp	149-154 °C (lit.)
Quality Level	200
SMILES string	Cl[H].NCCc1c[nH]c2ccc(O)cc12
solubility	0.1 M HCl: 22 mg/mL
	ethanol: 5.3 mg/mL
	H₂O: 17 mg/mL
storage temp.	2-8°C

Application:	Serotonin hydrochloride hasbeen used: to study the mechanisms of 5-hydroxytryptamine receptor antagonistsregulate fibrosis in liver spheroids, to study its effects on theextracellular-related-kinase (ERK) phosphorylation in human embryonic kidneycells, in transwell assay, wound healing assay and tumor allograft assay incolon carcinoma cell line
Biochem/physiol Actions:	Neurotransmitter.
Features and Benefits:	This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	Serotonin is a ubiquitous molecule found in all animals. It shows diverse effects in the central and peripheral nervous system (CAN/PNS). Serotonin acts as a hormone and as a mitogen. It is produced in the axon terminal present in the brain. Action potential induces the release of serotonin that diffuses across the synapse to turn on the post-synaptic receptors. Serotonin plays a crucialrole in development, respiration, thermoregulation, endocrine, cardiovascular, and gastrointestinal functions. It also plays a role in sensory perceptional behaviors such as the sleep-wake cycle, sex, mood, memory, aggression, pain sensitivity, learning, and cognition. Serotonin impacts several psychiatric disorders such as schizophrenia, anorexia nervosa, depression, and a range of anxiety disorders such as obsessive-compulsive disorder, panic attacks, and social phobia. Variations in serotonin levels are associated withimpulse-related disorders or personalities like substance abuse, gambling, attention deficit disorder, obsessive-control, and aggression.
Packaging:	1 g in glass bottle
Packaging:	100, 250 mg in glass bottle
Packaging:	25 mg in poly bottle
Preparation Note:	Solutions should be freshly prepared.

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 + H312 + H332 - H315 - H319 - H335
Precautionary statements	P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	22-26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
mp	149-154 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	12352200

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