Hypoxanthine
SIGMA/H9636 - powder, BioReagent, suitable for cell culture
Synonym: 6-Hydroxypurine
CAS Number: 68-94-0
Empirical Formula (Hill Notation): C5H4N4O
Molecular Weight: 136.11
EC Number: 200-697-3
MDL Number: MFCD00005725
Linear Formula: C5H4N4O
Product Type: Chemical
FT-IR Spectra for 6-Hydroxypurine.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H9636-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H9636-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H9636-25G
| assay | ≥99% |
| form | powder |
| InChI | 1S/C5H4N4O/c10-5-3-4(7-1- |
| InChI key | FDGQSTZJBFJUBT-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | O=C1NC=Nc2nc[nH]c12 |
| solubility | formic acid: water (2:1): 50 mg/mL |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies. |
| Application: | Hypoxanthine has been used: • as a supplement in HEPES (4-(2-hydroxyethyl)-1-pip • in the preparation of Dulbecco′s modified eagle′s medium (DMEM) + MXH for the selection of chimeric modified vaccinia virus ankara (MVA) • to generate superoxide anions • to prepare hybridoma selection and maintenance media. |
| Biochem/physiol Actions: | Hypoxanthine is capable of stimulating cell death. It can also induce reactive oxygen species (ROS). It results in endothelial dysfunction via apoptosis, stimulated by oxidative stress. |
| General description: | Hypoxanthine (6-hydroxypurine), a purine derivative is a naturally occurring compound. It is the deaminated form of adenine and a breakdown product of adenosine monophosphate (AMP). |
| Packaging: | 1, 5, 25 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | >300 °C (lit.) |
| UNSPSC | 12352207 |