5-Hydroxy-L-tryptophan
SIGMA/H9772 - powder
Synonym: L-
CAS Number: 4350-09-8
Empirical Formula (Hill Notation): C11H12N2O3
Molecular Weight: 220.22
EC Number: 224-411-1
MDL Number: MFCD00064341
Linear Formula: C11H12N2O3
Product Type: Chemical
| assay | ≥98% (TLC) |
| color | white to faint beige |
| form | powder |
| InChI | 1S/C11H12N2O3/c12-9(11(15 |
| InChI key | LDCYZAJDBXYCGN-VIFPVBQESA |
| Quality Level | 200 ![]() |
| SMILES string | N[C@@H](Cc1c[nH]c2ccc(O)c |
| storage temp. | 2-8°C |
| technique(s) | HPLC: suitable |
| Application: | 5-Hydroxy-L-tryptophan has been used: • to inject experimental mice for serotonin detection • as a precursor of 5-hydroxytryptamine and injected in pregnant mice and neonatal rats for vital neutral red staining of lung slices • as a standard in citrate-acetate buffer for its use in high performance liquid chromatography (HPLC) analysis |
| Biochem/physiol Actions: | Hydroxylation of L-tryptophan occurs in the brain during serotonin synthesis. This is a step that controls the production of serotonin and also yields 5-hydroxy-l-tryptophan (5-HTP) as a metabolite. Thus, consumption 5-HTP, increases the serotonin level, which might result in depression, lack of sleep and severe headache. |
| Biochem/physiol Actions: | Immediate precursor of serotonin; |
| Disclaimer: | Light sensitive |
| General description: | 5-Hydroxy-L-tryptophan (5-HTP) is naturally found in Griffonia simplicifolia. |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264 - P270 - P301 + P310 - P405 - P501 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352209 |


