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5-Hydroxy-L-tryptophan

SIGMA/H9772 - powder

Synonym: L-2-Amino-3-(5-hydroxyindolyl)propionic acid; L-5-HTP

CAS Number: 4350-09-8
Empirical Formula (Hill Notation): C11H12N2O3
Molecular Weight: 220.22
EC Number: 224-411-1
MDL Number: MFCD00064341
Linear Formula: C11H12N2O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-H9772-100MG 100 mg
$56.10
1/EA
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45-H9772-250MG 250 mg
$86.00
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45-H9772-1G 1 g
$145.00
1/EA
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45-H9772-5G 5 g
$583.00
1/EA
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45-H9772-25G 25 g
$1010.00
1/EA
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H9772-1G

 

assay ≥98% (TLC)
color white to faint beige
form powder
InChI 1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1
InChI key LDCYZAJDBXYCGN-VIFPVBQESA-N
Quality Level 200 
SMILES string N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(O)=O
storage temp. 2-8°C
technique(s) HPLC: suitable
Application: 5-Hydroxy-L-tryptophan has been used:
• to inject experimental mice for serotonin detection
• as a precursor of 5-hydroxytryptamine and injected in pregnant mice and neonatal rats for vital neutral red staining of lung slices
• as a standard in citrate-acetate buffer for its use in high performance liquid chromatography (HPLC) analysis

Biochem/physiol Actions: Hydroxylation of L-tryptophan occurs in the brain during serotonin synthesis. This is a step that controls the production of serotonin and also yields 5-hydroxy-l-tryptophan (5-HTP) as a metabolite. Thus, consumption 5-HTP, increases the serotonin level, which might result in depression, lack of sleep and severe headache.
Biochem/physiol Actions: Immediate precursor of serotonin; L-aromatic amino acid decarboxylase substrate.
Disclaimer: Light sensitive
General description: 5-Hydroxy-L-tryptophan (5-HTP) is naturally found in Griffonia simplicifolia.
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352209

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