Anti-URGCP antibody produced in rabbit
SIGMA/HPA020134 - Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2
Synonym: Anti-AC004985.2-1; Anti-HBV X protein up-regulated gene 4 protein; Anti-HBxAg up-regulated gene 4 protein; Anti-Protein URG4; Anti-URG4
Product Type: Chemical
Western Blotting JOURNAL CITATION: URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. By: Zhang, L., Huang, H., et al. in BMC Cancer, 2014. PubMed ID: 25427922 Image collected and cropped by CiteAb from the following publication, (http://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-885), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Immunohistochemistry JOURNAL CITATION: URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. By: Zhang, L., Huang, H., et al. in BMC Cancer, 2014. PubMed ID: 25427922 Image collected and cropped by CiteAb from the following publication, (http://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-885), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Western Blotting JOURNAL CITATION: URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. By: Zhang, L., Huang, H., et al. in BMC Cancer, 2014. PubMed ID: 25427922 Image collected and cropped by CiteAb from the following publication, (http://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-885), provided under a CC-BY license. Image might reflect a new usage that is not reflected in claims on product description or independently verified by Merck KGaA, Darmstadt, Germany. For Research Use Only. Not for use in diagnostic procedures.
Immunohistochemistry Immunohistochemical staining of human smooth muscle shows cytoplasmic positivity in smooth muscle cells.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| immunogen sequence | LIPVLKIDHSHVLVKVSSTDSDSFV |
| product line | Prestige Antibodies® Powered by Atlas Antibodies |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50- 1:200 |
| Application: | Anti-URGCP antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project  . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige . |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) Western Blotting (1 paper) |
| Biochem/physiol Actions: | Upregulator of cell proliferation (URGCP) is overexpressed in cervical cancer and it is associated with the growth of cancer cells. URGCP also enhances the growth of other carcinomas like hepatocellular carcinoma. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section. Every Prestige Antibody is tested in the following ways: • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues. • Protein array of 364 human recombinant protein fragments. |
| General description: | Upregulator of cell proliferation (URGCP) is a 104kDa protein and the gene associated with it is localized on human chromosome 7p13. |
| Immunogen: | Protein URG4 recombinant protein epitope signature tag (PrEST) |
| Legal Information: | Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | Corresponding Antigen APREST74937 |
| Physical form: | Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |