Formalin solution, neutral buffered, 10%
SIGMA/HT501128 - histological tissue fixative
Synonym: Formaldehyde; Methanal
MDL Number: MFCD00003274
Product Type: Chemical
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| application(s) | hematology histology |
| biological source | synthetic |
| color | colorless |
| concentration | 10% formalin (approx. 4% formaldehyde) |
| density | 1.080 g/cm3 |
| InChI | 1S/CH2O/c1-2/h1H2 |
| InChI key | WSFSSNUMVMOOMR-UHFFFAOYSA |
| pH | 6.90-7.10 |
| Quality Level | 200  |
| SMILES string | [O-]#[C+H2] |
| storage temp. | room temp |
| Application: | Formalin solution, neutral buffered, 10% has been used as a popular general purpose histological fixative to fix tissues. |
| Application: | Formalin solution, neutral buffered, 10% has been used in oil-red-o staining for the differentiation of 3T3-L1 preadipocyte cell line and mouse embryonic fibroblasts into adipocytes. It has been used in the histological analysis of rabbit′s eye and diabetic rat intestine. |
| Application: | Popular general purpose histological fixative. |
| General description: | 10% Neutral buffered formalin (NBF) is the most commonly used fixative throughout the world for light microscopy and is a somewhat forgiving fixative. 10% NBF is well suited for large throughput laboratories, and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue. Formalin fixation is thought to form between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining. |
| Physical form: | Neutral buffered solution |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H317 - H341 - H350 |
| Precautionary statements | P201 - P280 - P301 + P312 + P330 - P333 + P313 |
| Hazard Codes | T |
| Risk Statements | 45-20/21/22-43-68 |
| Safety Statements | 53-36/37-45 |
| WGK Germany | WGK 3 |
| Flash Point(F) | 185.0 °F |
| Flash Point(C) | 85 °C |
| Density | 1.080 g/cm3 |
| Storage Temp. | room temp |
| UNSPSC | 12352114 |