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Imipenem monohydrate

SIGMA/I0160 - ≥98% (HPLC)

Synonym: (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate; Primaxin monohydrate; Tienam monohydrate

CAS Number: 74431-23-5
Empirical Formula (Hill Notation): C12H17N3O4S · H2O
Molecular Weight: 317.36
EC Number: 264-734-5
MDL Number: MFCD09753321
Linear Formula: C12H17N3O4S · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I0160-5MG 5 mg
 $190.00
1/EA		 Add To Favorites
45-I0160-25MG 25 mg
 $752.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum mycobacteria
assay ≥98% (HPLC)
color white
form powder
InChI 1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
InChI key GSOSVVULSKVSLQ-JJVRHELESA-N
mode of action cell wall synthesis | interferes
originator Merck & Co., Inc., Kenilworth, NJ, U.S.
Quality Level 100 
SMILES string O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
storage temp. −20°C
Application: Imipenem monohydrate has been used to determine the resistance profiles of Pseudomonas aeruginosa isolates. It has also been used in susceptibility testing against Acinetobacter baumannii.
Biochem/physiol Actions: Imipenem is found effective against gram positive and negative aerobes and anaerobes. Imipenem is often combined with cilastatin, to inhibit its metabolism in kidney.
Biochem/physiol Actions: Imipenem monohydrate is a broad spectrum B-lactam antibiotic.
Biochem/physiol Actions: Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.
Features and Benefits: This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S. . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Chemical structure: ß-lactam
Packaging: 25 mg in poly bottle
Packaging: 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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