Interleukin-18 from rat
SIGMA/I0531 - >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
MDL Number: MFCD01867247
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | >97% (SDS-PAGE) |
| biological source | rat |
| form | lyophilized powder |
| impurities | endotoxin, tested |
| mol wt | predicted mol wt ~18.4 kDa |
| packaging | pkg of 25 μg |
| potency | 10-60 ng/mL ED50 |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −20°C |
| UniProt accession no. | Q16552  |
| Analysis Note: | The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells. |
| Biochem/physiol Actions: | Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells. |
| Physical form: | Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >97% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |