Interleukin-4 from mouse
SIGMA/I1020 - IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym: Interleukin-4; mIL-4; mIL-4; Interleukin-4 human
MDL Number: MFCD00166698
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | ≥98% (SDS-PAGE) |
| biological source | mouse |
| form | lyophilized powder |
| impurities | <0.1 EU/μg |
| mol wt | ~13.5 kDa |
| packaging | pkg of 5 μg |
| potency | 0.1-2.0 ng/mL ED50/EC50 |
| quality | endotoxin tested |
| recombinant | expressed in E. coli |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P07750   |
| Analysis Note: | The proliferative activity is tested in culture using mouse HT-2 cells. |
| Application: | Interleukin-4 from mouse has been used: • as a component of cell culture media for class switch recombination assay • to study its therapeutic benefits for mucosal healing • as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11) |
| Biochem/physiol Actions: | Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific. |
| Biochem/physiol Actions: | Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific. |
| Physical form: | Lyophilized, 0.2 μm filtered, with no additives. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |