Monoclonal Anti-Interferon-γ antibody produced in rat
SIGMA/I1142 - clone 37895, purified immunoglobulin, lyophilized powder
Synonym: Anti-IFN-γ
MDL Number: MFCD00165744
Product Type: Chemical
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| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rat |
| clone | 37895, monoclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| isotype | IgG2a |
| Quality Level | 200  |
| species reactivity | mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| neutralization: suitable | |
| western blot: suitable | |
| UniProt accession no. | P01580  |
| Application: | Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA. |
| Biochem/physiol Actions: | The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ. |
| General description: | Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ. |
| Immunogen: | recombinant mouse IFN-γ. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose. |
| Preparation Note: | Purified from cell culture supernatant using protein G. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |