Indatraline hydrochloride
SIGMA/I119 - solid
Synonym: (±)-trans-
CAS Number: 96850-13-4
Empirical Formula (Hill Notation): C16H15Cl2N · HCl
Molecular Weight: 328.66
MDL Number: MFCD00083178
Linear Formula: C16H15Cl2N · HCl
Product Type: Chemical
| color | white |
| form | solid |
| InChI | 1S/C16H15Cl2N.ClH/c1-19-1 |
| InChI key | QICQDZXGZOVTEF-MELYUZJYSA |
| Quality Level | 100  |
| SMILES string | Cl.CN[C@@H]1C[C@@H](c2ccc |
| solubility | H2O: 2 mg/mL |
| storage temp. | 2-8°C |
| Application: | Indatraline hydrochloride has been used: • as a competitive inhibitor of 3H-dopamine ([3H]DA) to study its effects on trans-activator of transcription (Tat) protein on cocaine-induced inhibition of uptake of [3H]DA • as a dopamine transport blocker to study its effects on trace amine-associated receptor 1 (TAAR1)-transfected mice cells • as a nonselective monoamine transport inhibitor to study its anti-angiogenic activities in glioblastoma multiforme (GBM) |
| Biochem/physiol Actions: | Indatraline is a non-selective monoamine transport inhibitor. It inhibits the reuptake of neurotransmitters, such as serotonin, norepinephrine and dopamine. It exhibits anti-depressant and anti-angiogenic effects. Indatraline also plays a role in inducing autophagy. |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Legal Information: | Sold with the permission of H. Lundbeck A/S. |
| Packaging: | 10, 25, 100 mg in glass bottle |
| Symbol |  GHS09 |
| Signal word | Warning |
| Hazard statements | H400 |
| Precautionary statements | P273 |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |