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ICI 118,551 hydrochloride

SIGMA/I127 - ≥98% (HPLC), powder

Synonym: (2R,3R)-rel-3-isopropylamino-1-(7-methylindan-4-yloxy)-butan-2-ol hydrochloride

CAS Number: 72795-01-8
Empirical Formula (Hill Notation): C17H27NO2 · HCl
Molecular Weight: 313.86
MDL Number: MFCD00153812
Linear Formula: C17H27NO2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I127-5MG 5 mg
 $290.00
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45-I127-25MG 25 mg
 $1030.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I127-25MG

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C17H27NO2.ClH/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17;/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3;1H/t13-,16-;/m0./s1
InChI key KBXMBGWSOLBOQM-LINSIKMZSA-N
Quality Level 100 
SMILES string Cl.CC(C)N[C@@H](C)[C@@H](O)COc1ccc(C)c2CCCc12
solubility H2O: >10 mg/mL
storage condition desiccated
Application: ICI 118,551 hydrochloride has been used:
• to block β-adrenergic signaling in various experiments
• to counteract degradation by endogenous T-lymphocyte monoamine oxidases
• to determine the specific receptor subtype necessary for isoproterenol to induce up-regulation of gene transcripts
Biochem/physiol Actions: ICI 118,551 has been used to treat vasomotor migraines and somatic troubles related to anxiety state.
Biochem/physiol Actions: ICI 118,551 hydrochloride is a highly selective β2-adrenoceptor antagonist.
Disclaimer: Hygroscopic
Features and Benefits: This compound is featured on the β-Adrenoceptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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