Iturin A from Bacillus subtilis
SIGMA/I1774 - ≥95% (HPLC)
CAS Number: 52229-90-0
MDL Number: MFCD01094135
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I1774-1MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I1774-5MG
| antibiotic activity spectrum | fungi |
| assay | ≥95% (HPLC) |
| biological source | Bacillus subtilis |
| color | white to yellow |
| form | powder |
| mode of action | cell membrane | interferes |
| Quality Level | 200  |
| solubility | ethanol: soluble 9.80-10.20 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | microbiological culture: suitable |
| Application: | Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus). |
| Biochem/physiol Actions: | IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes. |
| Other Notes: | A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids. |
| Packaging: | 1, 5 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |