Isocitric Dehydrogenase (NADP) from porcine heart
SIGMA/I1877 - Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)
Synonym: threo-Ds-Isocitrate: NADP+ oxidoreductase; ICDH; IDH
CAS Number: 9028-48-2
EC Number: 232-835-3
MDL Number: MFCD00131420
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I1877-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I1877-1G
| biological source | Porcine heart |
| form | solid |
| Quality Level | 200  |
| specific activity | 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) |
| storage temp. | −20°C |
| type | Type I |
| Analysis Note: | Crude |
| Biochem/physiol Actions: | Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers. |
| Other Notes: | One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C. |
| Packaging: | 1 g in poly bottle |
| Packaging: | 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 1.1.1.42 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |