3-Indoleacrylic acid
SIGMA/I2273 - BioReagent, ≥98% (HPLC)
Synonym: 3-(3-Indolyl)acrylic acid; IAA
CAS Number: 1204-06-4
Empirical Formula (Hill Notation): C11H9NO2
Molecular Weight: 187.19
EC Number: 214-872-7
MDL Number: MFCD00005633
Linear Formula: C11H9NO2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I2273-1G
| assay | ≥98% (HPLC) |
| form | powder |
| grade | Molecular Biology |
| InChI | 1S/C11H9NO2/c13-11(14)6-5 |
| InChI key | PLVPPLCLBIEYEA-AATRIKPKSA |
| mol wt | 187.19 g/mol |
| product line | BioReagent |
| Quality Level | 100  |
| SMILES string | OC(=O)C=Cc1c[nH]c2ccccc |
| storage temp. | room temp |
| Application: | 3-Indoleacrylic acid has been used in the induction of ribokinase expression in E. coli. |
| Biochem/physiol Actions: | 3-Indoleacrylic acid (IAA) is metabolized from tryptophan and this conversion is carried out by gut microflora. 3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. The IAA induced expression system requires the gene of interest cloned in plasmids containing the trp promoter. It promotes the barrier functionality of the intestinal epithelial cells. IAA also favors anti-inflammatory response and is regarded as a potential therapeutic to treat inflammatory bowel disease (IBD). It is also implicated in a variety of cellular processes including apoptosis, autophagy, cell proliferation and migration. In tumor cells, IAA is also reported to hinder tryptophan metabolism. |
| General description: | 3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. This expression system requires that the gene of interest is cloned in plasmids containing the trpE promoter. |
| Packaging: | 1, 5 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352106 |