IPA-3
SIGMA/I2285 - ≥95% (HPLC), powder
Synonym: 1,1′-Disulfanediyldinaphthalen-2-ol
CAS Number: 42521-82-4
Empirical Formula (Hill Notation): C20H14O2S2
Molecular Weight: 350.45
MDL Number: MFCD00388917
Linear Formula: C20H14O2S2
Product Type: Chemical
| assay | ≥95% (HPLC) |
| color | off-white to yellow |
| form | powder |
| InChI | 1S/C20H14O2S2/c21-17-11-9 |
| InChI key | RFAXLXKIAKIUDT-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | Oc1ccc2ccccc2c1SSc3c(O)cc |
| solubility | DMSO: >20 mg/mL |
| H2O: insoluble | |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | IPA-3 is an allosteric inhibitor of Pak1. |
| Biochem/physiol Actions: | IPA-3 is an allosteric inhibitor of Pak1. It binds to autoinhibitory domain of Pak1 (p21 activated kinase), highly selective amongst kinases. Pak1 is implicated in tumorigenesis and metastasis. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol | ![]() GHS05,GHS09 |
| Signal word | Danger |
| Hazard statements | H318 - H410 |
| Precautionary statements | P273 - P280 - P305 + P351 + P338 - P501 |
| Hazard Codes | Xi,N |
| Risk Statements | 41-50/53 |
| Safety Statements | 26-39-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |



