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Ifenprodil (+)-tartrate salt

SIGMA/I2892

Synonym: α-(4-Hydroxyphenyl)-β-methyl-4-benzyl-1-piperidineethanol (+)-tartrate salt

CAS Number: 23210-58-4
Empirical Formula (Hill Notation): C42H54N2O4 · C4H6O6
Molecular Weight: 800.98
EC Number: 245-493-5
MDL Number: MFCD01529999
Linear Formula: (C21H27NO2)2 · C4H6O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I2892-10MG 10 mg
 $98.10
1/EA		 Add To Favorites
45-I2892-25MG 25 mg
 $233.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I2892-25MG

 

InChI 1S/2C21H27NO2.C4H6O6/c2*1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17;5-1(3(7)8)2(6)4(9)10/h2*2-10,16,18,21,23-24H,11-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
InChI key DMPRDSPPYMZQBT-UHFFFAOYSA-N
Quality Level 200 
SMILES string OC(C(O)C(O)=O)C(O)=O.CC(C(O)c1ccc(O)cc1)N2CCC(CC2)Cc3ccccc3.CC(C(O)c4ccc(O)cc4)N5CCC(CC5)Cc6ccccc6
storage temp. room temp
Application: Ifenprodil (+)-tartrate salt has been used:
• to test the action in a KCl-induced cortical spreading depression (CSD) animal
• to study its effects on electrophysiological properties and spontaneous spikes in neocortical pyramidal cells
• to investigate its therapeutic effects
Biochem/physiol Actions: NMDA antagonist acting at the polyamine site; neuroprotective agent; α-adrenergic central and peripheral vasodilator; α2 adrenergic receptor ligand.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Glutamate Receptors (Ion Channel Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Ifenprodil is a phenylethanolamine, which stimulates blood circulation. It has anticonvulsant and antinociceptive properties. Ifenprodil is used to treat posttraumatic stress disorder, cerebrovascular diseases and peripheral arterial obliterative disease. It blocks G protein-coupled inwardly-rectifying potassium channels (GIRKs) and interacts with α1 adrenergic, N-methyl-D-aspartate and serotonin receptors.
Packaging: 10 mg in poly bottle
Packaging: 25 mg in glass bottle
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. room temp
UNSPSC 12352200

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