Inosine

SIGMA/I4125 - ≥99% (HPLC)

Synonym: (−)-Inosine; Hypoxanthine 9-β-D-ribofuranoside

CAS Number: 58-63-9
Empirical Formula (Hill Notation): C₁₀H₁₂N₄O₅
Molecular Weight: 268.23
EC Number: 200-390-4
MDL Number: MFCD00066770
Linear Formula: C₁₀H₁₂N₄O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-I4125-1G	1 g	$60.40 1/EA	Add To Favorites
45-I4125-5G	5 g	$78.80 1/EA	Add To Favorites
45-I4125-10G	10 g	$98.00 1/EA	Add To Favorites
45-I4125-25G	25 g	$123.00 1/EA	Add To Favorites
45-I4125-100G	100 g	$379.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: I4125-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% (HPLC)
InChI	1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1
InChI key	UGQMRVRMYYASKQ-KQYNXXCUSA-N
mp	222-226 °C (dec.) (lit.)
Quality Level	200
SMILES string	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3C(=O)NC=Nc23

Application:	Inosine has been used: • as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines. • as a component in holidic (synthetic) medium and in larval two-choice preference assay. • as a reference standard in mass spectroscopy.
Biochem/physiol Actions:	Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.
General description:	Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine. Incorporation of inosine in place of guanine modulates translational events. Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress. It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors. Inosine is also used for treating sepsis in infections.
Packaging:	1, 5, 10, 25, 100 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
mp	222-226 °C (dec.) (lit.)
UNSPSC	41106305

To Order From a Quote