Interleukin-2 from mouse
SIGMA/I4161 - IL-2, recombinant, expressed in E. coli, carrier free
Synonym: IL-2; Interleukin-2; T-cell growth factor; mIL-2; mIL-2; IL-2; T-cell growth factor
MDL Number: MFCD00164816
Product Type: Chemical
SDS-PAGE Interleukin-2 from Mouse (Cat. No. I4161) was assessed on SDS-PAGE.
Bioassay EC50 is defined as the effective concentration of Interleukin-2 that elicits a 50% attachment factor in cell based bioassay.
| assay | ≥97% (SDS-PAGE) |
| biological source | mouse |
| color | white |
| form | lyophilized powder |
| impurities | ≤0.200ng/ml |
| mol wt | 17.2 kDa |
| packaging | pkg of 20 μg |
| pkg of 5X20 μg | |
| potency | ≤0.2 ng/mL ED50 |
| quality | endotoxin tested |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P04351  |
| Biochem/physiol Actions: | Interleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. |
| Physical form: | Lyophilized with no additives. |
| Preparation Note: | Centrifuge vial prior to opening. Reconstitute the contents of the vial in water to a concentration range of 0.1-1.0 mg/mL. |
| Preparation Note: | IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |