Interferon-γ from mouse
SIGMA/I4777 - ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym: IFN-γ
MDL Number: MFCD00131391
Product Type: Chemical
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| assay | ≥98% (SDS-PAGE) |
| biological source | mouse |
| color | white |
| form | lyophilized powder |
| impurities | endotoxin, tested |
| mol wt | protein 15.6 kDa |
| packaging | pkg of 0.1 mg |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| solubility | water: soluble 1.000 mL, clear, colorless |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P01580  |
| Analysis Note: | The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells. |
| Application: | Interferon-γ from mouse has been used: • for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c+ (CD11 antigen-like family member C) lung macrophages • for stimulation of murine macrophages to induce the production of nitrite and nitrate • to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation |
| Biochem/physiol Actions: | Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. |
| Physical form: | Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |