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Idazoxan hydrochloride

SIGMA/I6138

Synonym: (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride; RX 781094

CAS Number: 79944-56-2
Empirical Formula (Hill Notation): C11H12N2O2 · HCl
Molecular Weight: 240.69
MDL Number: MFCD00069293
Linear Formula: C11H12N2O2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I6138-50MG 50 mg
 $126.00
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45-I6138-100MG 100 mg
 $168.00
1/EA		 Add To Favorites

 

InChI 1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
InChI key MYUBYOVCLMEAOH-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.C1CN=C(N1)C2COc3ccccc3O2
solubility H2O: 50 mg/mL
Application: Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.
Biochem/physiol Actions: α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes Xn
Risk Statements 22
Safety Statements 7
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352200

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