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ISCK03

SIGMA/I6410 - ≥98% (HPLC), solid

Synonym: Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]; [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide

CAS Number: 945526-43-2
Empirical Formula (Hill Notation): C19H21N3O2S
Molecular Weight: 355.45
MDL Number: MFCD12031591
Linear Formula: C19H21N3O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I6410-5MG 5 mg
 $136.00
1/EA		 Add To Favorites
45-I6410-25MG 25 mg
 $371.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color yellow
form solid
InChI 1S/C19H21N3O2S/c1-19(2,3)15-4-10-18(11-5-15)25(23,24)21-16-6-8-17(9-7-16)22-13-12-20-14-22/h4-14,21H,1-3H3
InChI key XQABBHBFHWHMKF-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)-n3ccnc3
solubility DMSO: ≥20 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Biochem/physiol Actions: ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner.
Biochem/physiol Actions: ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. ISCK03 inhibits SCF (stem cell factor)-induced c-kit phosphorylation in 501mel human melanoma cells. Complete inhibition was observed with 1 and 5 μM ISCK03.
Features and Benefits: This compound is featured on the PDGFR  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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