Anti-Interleukin-2 antibody produced in goat
SIGMA/I7784 - affinity isolated antibody, lyophilized powder
Synonym: Anti-IL-2
MDL Number: MFCD00675261
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 100  |
| species reactivity | rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | neutralization: suitable |
| western blot: 0.1-0.2 μg/mL | |
| UniProt accession no. | P04351  |
| Application: | Anti-interleukin-2 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. The antibody is suitable for murine IL-2 neutralization assays. |
| General description: | Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle Monoclonal Anti-Interleukin-2 recognizes murine Interleukin-2. It does not react with human IL-2, but will react with rabbit IL-2 at a 100x higher IgG concentration. |
| Immunogen: | purified, E. coli-derived recombinant mouse interleukin-2. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |