2-Iodosobenzoic acid
SIGMA/I8000
Synonym: IBA
CAS Number: 304-91-6
Empirical Formula (Hill Notation): C7H5IO3
Molecular Weight: 264.02
EC Number: 206-159-4
MDL Number: MFCD00002401
Linear Formula: OIC6H4CO2H
Product Type: Chemical
| assay | ≥98% (TLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C7H5IO3/c9-7(10)5-3-1- |
| InChI key | IFPHDUVGLXEIOQ-UHFFFAOYSA |
| mp | 230 °C (dec.) (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | OC(=O)c1ccccc1[I]=O |
| storage temp. | −20°C |
| Application: | For cleavage of tryptophanyl peptide bonds. |
| Biochem/physiol Actions: | 2-Iodosobenzoic acid (IBA) may be used to study enzyme structure and activity. IBA is used as an oxidant which oxidizes vicinal sulfhydryls to disulfides (cysteine residues) within enzymes leading to their inactivation or conformational changes. IBA is also used to cleave tryptophanyl peptide bonds. |
| Packaging: | 1, 5 g in poly bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥98% (TLC) |
| mp | 230 °C (dec.) (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |


