L-N6-(1-Iminoethyl)lysine dihydrochloride
SIGMA/I8021
Synonym: L-Lysine ω-acetamidine dihydrochloride; L-NIL dihydrochloride
CAS Number: 159190-45-1
Empirical Formula (Hill Notation): C8H17N3O2 · 2 HCl
Molecular Weight: 260.16
MDL Number: MFCD00270890
Linear Formula: C8H17N3O2 · 2 HCl
Product Type: Chemical
| assay | ≥97% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C8H17N3O2.2ClH/c1-6(9) |
| InChI key | OQIBCXRAFAHXMM-KLXURFKVSA |
| SMILES string | Cl.Cl.CC(=N)NCCCC[C@H](N) |
| solubility | water: 50 mg/mL, clear, colorless |
| storage temp. | −20°C |
| Application: | L-N6-(1-Iminoethyl)lysine dihydrochloride has been used as an inducible nitric oxide synthase (iNOS) inhibitor: • to study its effects on leptin-induced modulation of fibronectin type III domain-containing five (FNDC5)/irisin in myocytes and fat cells of murine • to study its effects on leptin-induced inflammation in hepatocytes • to block the production of nitric oxide in mice bone marrow mesenchymal stromal cells (BMSCs) |
| Biochem/physiol Actions: | Selective inhibitor of inducible nitric oxide synthase (iNOS). |
| Packaging: | 10 mg in glass insert |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |