Anti-Human IgG (whole molecule) antibody produced in rabbit
SIGMA/I8635 - whole antiserum
MDL Number: MFCD00162452
Product Type: Chemical
Immunohistochemistry Formalin-fixed, paraffin-embedded human appendix tissue sections stained with 1:100 Anti-Human IgG (whole molecule) antibody produced in Rabbit (Cat. No. I8635) followed by Anti-Rabbit IgG (whole molecule)-Peroxidase antibody produced in Goat (Cat. No. A0545).
Immunohistochemistry Formalin fixed, paraffin-embedded Human tonsil were stained with 1:100 Anti-Human IgG (whole molecule) antibody produced in Rabbit (Cat. No. I8635) followed by 1:25 Monoclonal Anti-Rabbit Immunoglobulins-FITC antibody produced in Mouse, Clone: RG-16 (Cat. No. F4890).
ELISA Anti-Human IgG (whole molecule) antibody produced in Rabbit (Cat. No. I8635), followed by 1:5,000 Anti-Rabbit IgG (whole molecule)-Peroxidase antibody produced in Goat (Cat. No. A0545), was serially diluted to detect Human IgG by indirect ELISA.
| antibody form | whole antiserum |
| antibody product type | secondary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| contains | 15 mM sodium azide |
| Quality Level | 300  |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:60,000 |
| quantitative precipitin assay: 2.5 mg/mL |
| Application: | Anti-Human IgG (whole molecule) antibody produced in rabbit has been used in enzyme linked immunosorbent assay. |
| Biochem/physiol Actions: | IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. |
| Biochem/physiol Actions: | IgG1 deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections, IgG3 mediates effector functions and IgG4 is associated with asymptomatic infection. IgG antibodies have enormous therapeutic potential and the Fc region is for the development of therapeutic antibody. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobin has two heavy (H) and two light (L) chains, held together by disulphide linkages. Each light chain comprises of one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal regions. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4. |
| Preparation Note: | delipidized |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |