IgG from mouse serum
SIGMA/I8765 - technical grade, ≥80% (SDS-PAGE), buffered aqueous solution
Synonym: Mouse IgG
MDL Number: MFCD00212351
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | ≥80% (SDS-PAGE) |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| grade | technical grade |
| Quality Level | 300  |
| shipped in | dry ice |
| storage temp. | −20°C |
| technique(s) | ChIP: suitable |
| immunohistochemistry: suitable |
| Application: | Technical grade IgG may be used as an economical alternative to the reagent grade immunoglobulins in applications where high purity is not required. IgG from mouse serum was used as negative control in immunohistochemistry at a concentration of 2 μg/ml. It was used as irrelevant control in chromatin immunoprecipitaion assay (10 μg). |
| Biochem/physiol Actions: | Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections IgG from mouse serum specifically recognizes IgG from mouse. Mouse IgG is purified from normal mouse serum by fractionation. |
| General description: | Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. A immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 5 mg in glass insert |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37-60 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥80% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |