Interferon β from rat
SIGMA/I8907 - ≥95%, recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture
Synonym: IFN-β
MDL Number: MFCD04040885
Product Type: Chemical
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| assay | ≥95% |
| biological source | rat |
| concentration | ≥100000 units/mL |
| form | lyophilized powder |
| mol wt | ~20 kDa |
| packaging | pkg of 1 vial |
| Quality Level | 200  |
| recombinant | expressed in CHO cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P70499  |
| Analysis Note: | The biological activity is determined in the cytopathic effect inhibition assay using rat epithelial-like (RATEC) cells with vesicular stomatitis virus (VSV). The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. Since there is no international rat interferon β standard, units are determined with respect to the NIH international standard reference for mouse interferon α/β. |
| Biochem/physiol Actions: | Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. |
| Biochem/physiol Actions: | Interferon β belongs to the type 1 interferon family pf proteins. It is also needed for the inhibition of tumor cell growth via cell death, S-phase increase and mediating differentiation. It is also important for bone homeostasis. |
| Physical form: | Lyophilized from phosphate buffered saline (PBS) containing 125 mM trehalose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |