Juvenile hormone III
SIGMA/J2000 - ≥65%, liquid, non-sterile
Synonym: Methyl farnesoate, 10,11-epoxide; C16-Juvenile Hormone; JH-III; Manduca hormone; trans,trans-
CAS Number: 24198-95-6
Empirical Formula (Hill Notation): C16H26O3
Molecular Weight: 266.38
EC Number: 246-072-9
MDL Number: MFCD00135990
Linear Formula: C16H26O3
Product Type: Chemical
| assay | ≥65% (HPLC) |
| biological source | synthetic (organic) |
| concentration | ≥65% |
| form | liquid |
| InChI | 1S/C16H26O3/c1-12(9-10-14 |
| InChI key | QVJMXSGZTCGLHZ-ZPLWXOMKSA |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | COC(=O)C=C(/C)CCC=C(/C) |
| sterility | non-sterile |
| storage temp. | −20°C |
| technique(s) | activity assay: suitable |
| Application: | Juvenile hormone III has been used to: • study the effect of juvenile hormone on mictic (sexual) female production of the rotifer Brachionus plicatilis Muller • study the effect of juvenile hormone on head GB19811 (putative Takeout/juvenile hormone binding protein) mRNA levels in adult honeybees • study the effect of juvenile hormone on gonadotropic and physiological functions in bumblebee Bombus terrestris |
| Biochem/physiol Actions: | Controls the larval metamorphosis of insects, including the retention of juvenile characteristics. |
| Biochem/physiol Actions: | JHBPs (JH-binding proteins) protect JH (juvenile hormone) from JH esterase- and epoxide hydrolase-mediated degradation. They also help in delivering JH to target tissues.Juvenile hormones(JHs) are a group of acyclic sesquiterpenoids, and in some insect lineages, the farnesol backbone of these compounds undergoes chemical modification to produce a homologous series of hormones. JH is essential for insect development and reproduction in every aspect. It plays a key role in metamorphosis and caste determination in social insects. It modulates behavior, polyphenism, larval and adult diapause, and ovarian development. The sesquiterpenoid backbone of juvenile hormone III (JH III) is biosynthesized through the classical mevalonate (MVA) pathway in cockroaches. |
| General description: | Research Area: Cell Signaling Juvenile hormone III (JH III) is the most prevalent juvenile hormone (JH) found in insects. |
| Hazard statements | H413 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥65% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |